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pentobarbital will minimize the extent or influence of atazanavir by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Significance Unidentified.pentobarbital will lower the extent or influence of bortezomib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.pentobarbital decreases amounts of vandetanib by affe